Established in 1891, The Bank of Missouri originated with a group of Perryville neighbors aiming to prioritize local needs. Initially operating from a single branch for over a century, the bank evolved to meet the diverse financial goals of the community. The transition from The Bank of Perryville to The Bank of Missouri signified broader aspirations. Expanding to Cape Girardeau in 1997, the bank continued to grow, reaching various regions across the state. Today, with a network of branches and modern financial services, The Bank of Missouri maintains its community-focused ethos, seeing customers as neighbors and addressing their financial needs with both familiarity and capability.